Research
Current Research
Vitreous Floaters and Vision: Current Concepts and Management Paradigms
Vitrectomy For Floaters – Prospective Efficacy Analyses and Retrospective Safety Profile
The Underlying Anatomy of Vitreous and Its Role in Retinal Disease
Floater Vitrectomy – Retinal Physician
Vitreous
Dr. Sebag began conducting vitreous research as a medical student at the College of Physicians & Surgeons, Columbia University. Over the past 30 years this has been his passion and has resulted in an unparalleled expertise in this area. Considered one of the world’s pre-eminent experts in vitreous, Dr. Sebag has published widely in this area.
Publications on Vitreous
Age-Related Changes in Human Vitreous Structure
Age-Related Differences in Vitreoretinal Interface
Anatomie et physiologie du vitré et de l’interface vitréorétinienne
Anomalous Posterior Vitreous Detachment: A Unifying Concept in Vitreo-Retinal Disease
Classifying Posterior Vitreous Detachment: A New Way to Look at the Invisible
Floater Vitrectomy – Retinal Physician
Morphology and Ultrastructure of Human Vitreous Fibers
The Underlying Anatomy of Vitreous and Its Role in Retinal Disease
Vitreoschisis in Diabetic Macular Edema
Vitreous Anatomy, Aging, and Anomalous Posterior Vitreous Detachment
Vitreous Anatomy and Pathology
Pharmacologic Vitreolysis
Publications on Pharmacologic Vitreolysis
Chapter VI.A.Pharmacologic Vitreolysis
Is Pharmacologic Vitreolysis Brewing?
Molecular Biology of Pharmacologic Vitreolysis
Novel Vitreous Modulators for Pharmacologic Vitreolysis in the Treatment of Diabetic Retinopathy
Pharmacologic Vitreolysis – Retina
Pharmacologic Vitreolysis—Premise and Promise of the First Decade
The Emerging Role of Pharmacologic Vitreolysis – Retinal Physician, 2010
Diabetes
Publications
Abnormalities of Human Vitreous Structure in Diabetes
Biochemical Abnormalities in Vitreous of Humans With Proliferative Diabetic Retinopathy
Diabetic Vitreopathy (Guest Editorial) – Ophthalmology, 1996
Dynamic Light Scattering of Diabetic Vitreopathy
Effects of Pentoxifylline on Choroidal Blood Flow in Nonproliferative Diabetic Retinopathy
Novel Vitreous Modulators of Pharmacologic Vitreolysis in the Treatment of Diabetic Retinopathy
Raman Spectroscopy of Human Vitreous in Proliferative Diabetic Retinopathy
Age-Related Macular Degeneration (AMD)
Publications
Retinal Detachment
Publications
Apoptotic Photoreceptor Cell Death After Traumatic Retinal Detachment in Humans
Retinal S-Antigen in Human Subretinal Fluid
Current Eye Research – Neuron Specific Enolase
Letter to Editor on S-Antigen in Retinal Detachment
Long-term results of office-based pneumatic retinopexy using pure air
Macular Holes and Macular Pucker
Publications
Optic Nerve
Publications
Anterior Optic Nerve Blood Flow Decreases in Clinical Neurogenic Optic Atrophy
Anterior Optic Nerve Blood Flow in Experimental Optic Atrophy
Optic Disc Cupping in Arteritic Anterior Ischemic Optic Neuropathy Resembles Glaucomatous Cupping
Effects of Optic Atrophy on Retinal Blood Flow and Oxygen Saturation in Humans
L’effet de l’atrophie optique neurogénique sur le flux sanguin papillaire
Perioperative Risk Factors for Posterior Ischemic Optic Neuropathy
General Interest
Publications
Book Chapters
Chapters
Duanes Clinical Ophthalmology – Vitreous Biochemistry, Morphology, and Clinical Examination
Myopia & Related Diseases – Myopic Vitreopathy
Duanes Clinical – Surgical Anatomy
To See the Invisible: The quest of Imaging Vitreous
Vitreous Anatomy, Aging, and Anomalous Posterior Vitreous Detachment – Encyclopedia of the Eye
Vitreous Anatomy and Pathology
Imaging and Diagnostic Testing
Imaging of the Vitreous, Macula, & Retina
Using the newest technology for digital imaging, Dr. Sebag and Dr. Chong are supervising 4th year medical students and research fellows from USC, who are conducting research in collaboration with the Doheny Eye Institute and the New York Eye & Ear Infirmary, Harvard Medical School, and the University of Sydney in Australia. This powerful new imaging technology has been available at the VMR Institute since November of 2005 and has been used extensively in clinical care and research. The results have been presented at the American Academy of Ophthalmology, the Club Jules Gonin, the Retina Society, and the Association for Research and Vision in Ophthalmology (ARVO).
Publications
3-Dimensional Threshold Amsler Grid Testing
In collaboration with scientists at the Doheny Eye Institute and Caltech/JPL, Dr. Sebag is developing advanced diagnostic instrumentation to detect central visual field abnormalities in patients with macular degeneration, diabetic retinopathy, macular holes, macular pucker, central serous chorio-retinopathy, and retinal vein occlusions. Doheny Eye Institute medical students have been conducting studies at the VMR Institute with this new technology, and the research results have been presented at various meetings around the world. Currently, work is being directed to making this test available online so that patients will one day be able to test themselves at home.
Publications